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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis

Fig. 1

2-DG inhibited the increased glycolysis in LPS-stimulated peritoneal macrophages in vitro. a Uptake of the fluorescent glucose analogue 2-NBDG in the LPS-stimulated peritoneal macrophages, measured by flow cytometry. b Graphic representation of the mean fluorescence intensity shown in (a). ***p < 0.001, n = 3, two-tailed Student’s t test for unpaired data. Surplus glucose (c) and pH values (d) of the culture supernatants after stimulating peritoneal macrophages by LPS (50 ng/ml) with or without 2-DG for 18 h. *p < 0.05, **p < 0.01, ***p < 0.001, n = 4, one-factor analysis of variance (ANOVA). The results are expressed as mean ± SD

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