Fig. 3
From: Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis
Preventive treatment of 2-DG decreased Th1 and Th17 cells but increased Treg cells in vivo. MNCs of the lymph nodes were harvested from both groups on day 10 p.i. Th1 (CD4+IFN-γ+) cells (a), Th17 (CD4+IL-17+) cells (b), and Treg (CD4+CD25+Foxp3+) cells (c) were detected by flow cytometry. For Treg cell analysis, CD4+ cells were first gated. The results were expressed as mean ± SD (n = 4). *p < 0.05, **p < 0.01, two-tailed Student’s t test for unpaired data