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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Cellular and behavioral effects of lipopolysaccharide treatment are dependent upon neurokinin-1 receptor activation

Fig. 1

Effect of neurokinin-1 (NK1R) antagonism on LPS-induced increase in NFkB-DNA-binding activity in the hippocampus. Rats were treated with L822429 (30 mg/kg) 1 h prior to LPS (200 μg/kg) and sacrificed 2 h after LPS injection. a Electrophoretic mobility shift assay (EMSA) quantification: data expressed as percent of vehicle-saline control. b Representative image of EMSA results. n = 6/group. *p < 0.05, compared to the vehicle-saline, #p < 0.05 compared to the vehicle-LPS

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