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Table 2 Fold change of HLA expression induced by IFN-α and IFN-γ in each cell type analyzed

From: Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients

 

Fold change HLA-E (IFN-α)

Fold change HLA-E (IFN-γ)

Fold change HLA-ABC (IFN-α)

Fold change HLA-ABC (IFN-γ)

Fold change HLA-DR (IFN-α)

Fold change HLA-DR (IFN-γ)

B cells

1.733

1.503

1.286

1.202

0.979

1.041

CD4 T cells

1.790

1.514

1.554

1.267

0.921

1.070

CD8 T cells

1.609

1.343

1.510

1.207

0.976

1.098

NK cells

2.124

1.487

1.739

1.292

1.558

1.750

Monocytes

2.261

1.377

2.096

1.539

1.458

3.131

  1. Mean values of fold change in HLA-E, HLA-ABC, and HLA-DR expression in different cell types of both MS patients (n = 14) and controls (n = 11) after 24 h of IFN-α and IFN-γ stimulation
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Journal of Neuroinflammation

ISSN: 1742-2094