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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation

Fig. 4

Chronic exposure to TNFα does not alter the phagocytic and rhodopsin degradation capabilities of RPE cells. a Quantification of relative levels of photoreceptor outer segment (POS) binding and b POS internalization by RPE cells in the indicated culture conditions (n = 5/group one-way ANOVA, versus control, non-significant differences). c Western blot analysis of Rhodopsin and β-actin protein after 6 and 24 h of culture of primary porcine RPE cells (pretreated with 10-day TNF-α at 0.8, 4, and 20 ng/mL) and photoreceptor outer segments (POS)

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