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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation

Fig. 5

Chronic exposure to TNFα impairs the immunosuppressive function of RPE cells. a Representative pictures of human monocytes (hMos, human hematopoietic transcription factor (PU1) staining, green) and RPE nuclei (Hoechst, blue) and b automated quantification of the number of human monocytes in a 24-h co-culture with RPE cells with or without previous 10-day pre-treatment with TNFα (at 0.8, 4, and 20 ng/ml) (n = 5/group, one way ANOVA versus control ***P < 0.0005)

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