Fig. 6
From: Nitrosative damage during retrovirus infection-induced neuropathic pain
Nitrosative damage within DRG sensory neurons of LP-BM5-infected animals. Histochemistry to identify IB4-binding, NF200, nitrotyrosine, and DAPI was carried out on sections of DRG (L3-L5) at 10 weeks post-LP-BM5 infection. a Representative images depicting labelling of neuronal cells with IB4 (green), nitrotyrosine (red), DAPI (blue), and a merged image showing triple staining with IB4, nitrotyrosine, and DAPI. White arrows indicate the co-labeled neurons. b Representative images depicting labelling of neuronal cells with NF200 (green), nitrotyrosine (red), DAPI (blue), and a merged image showing triple staining with NF200, nitrotyrosine, and DAPI. White arrows indicate co-labeled neurons. Scale bar = 50 μm. c Graphical representation of the percentage of neurons showing double-immunolabeling for nitrotyrosine (NT) and IB4 in the DRG of LP-BM5-infected animals. d Column graph showing the percentage of neurons co-labeled with NT and NF200 in the DRG of LP-BM5-infected mice. n = 3–4 mice/group. Values are presented as mean ± SEM. *p < 0.05