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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Effects of dexamethasone on the Li-pilocarpine model of epilepsy: protection against hippocampal inflammation and astrogliosis

Fig. 2

Dexamethasone prevents neuroinflammation in the hippocampus. Pro-inflammatory and anti-inflammatory cytokines were measured by ELISA. Dexamethasone decreased TNFα (a), reversed IL-1β (b), and PGE-2 (c) levels at 1 day after treatment. Dexamethasone did not affect PGE2 (d) content at 56 days nor IL-10 levels at 1 day after treatment. At 56 days, dexamethasone increased IL-10 content. Values were expressed by mean ± standard error, of four to six animals per group. Data were analyzed by ANOVA, followed by the Tukey test. Bars without a common letter differ significantly, assuming p < 0.05

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