Fig. 7

Dexamethasone does not alter Kir 4.1 and AQP-4 astrocyte channel content in the hippocampus. Kir 4.1 and AQP-4 contents were determined by Western blot. Representative images of Kir 4.1 and AQP-4 in the hippocampus at 1 and 56 days after treatment (a, b). Chemiluminescent quantification of Kir 4.1 (c, d) and AQP-4 (e, f) protein/actin. Dexamethasone did not reverse the reduction in Kir 4.1 content in the hippocampus of SE animals at 1 day after treatment (c); however, dexamethasone prevented Kir4.1 content in SE animals at 56 days after treatment (d). No differences in AQP-4 channel expression were observed between groups (e, f). Values represent mean ± standard error, of four to six animals per group. Data were analyzed by ANOVA, followed by Tukey test. Bars without a common letter differ significantly, assuming p < 0.05