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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries

Fig. 4

Alpha beta T cell infiltration into the lumbar DR leptomeninges are specifically determined by LLNs after adult rat mSNIs. (A1–D1, A2–D2) Alpha beta T cell infiltration into the whole length of the L4 DR leptomeninges 7 days after mSNIs in prior lymphadenectomized or sham-operated animals to LLNs (n = 5/group). e Temporal dynamics of αβ T cell entry into the leptomeninges covering the proximal L4 DRs at the DR portions of the subarachnoid angles before and after mSNIs in prior lymphadenectomized or sham-operated animals to LLNs (n = 5/group). **P < 0.01, ***P < 0.001; after versus before mSNIs. #P < 0.05, ###P < 0.001; lymphadenectomy versus sham operation. DR dorsal root, DRG dorsal root ganglion, DRL dorsal root leptomeninges, LLN lumbar lymph node, LM leptomeninges, mSNI modified spared nerve injury, P parenchyma

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Journal of Neuroinflammation

ISSN: 1742-2094