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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Neonatal hyperglycemia induces CXCL10/CXCR3 signaling and microglial activation and impairs long-term synaptogenesis in the hippocampus and alters behavior in rats

Fig. 4

The acute effect of STZ-induced hyperglycemia on microgliosis and astrocytosis on P6. Representative photomicrographs of the hippocampal CA1 region at 10× stained for CD-11 from a control and b hyperglycemia groups. Scale bars = 250 μm. The number of CD-11-positive microglia was significantly increased in the hyperglycemia group (gray) relative to control (black), *p < 0.05 (c). Representative photomicrographs of the hippocampal CA1 region at 20× stained for S100β astrocytes from d control and e hyperglycemia groups. Scale bars = 100 μm. The number of S100β positive astrocytes was significantly increased in the hyperglycemia group (gray) relative to the control (black), p < 0.05 (f)

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Journal of Neuroinflammation

ISSN: 1742-2094