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Table 1 Clinicopathological characteristics of AIS and healthy controls

From: Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization

Characteristics

Controls (60)

AIS (60)

Age (years)

58.4 ± 6.9

62.2 ± 8.2

Sex

 Male

32

26

 Female

28

34

Weight (kg)

78.9 ± 6.3

81.3 ± 7.8

Height (m)

1.7 ± 0.1

1.7 ± 0.1

BMI

26.8 ± 3.1

27.1 ± 3.4

NIHSS

12.6 ± 2.4

Risk factors (no)

 Hypertension, n (%)

46 (76.7%)

 CHD, n (%)

22 (36.7%)

Laboratory findings

 WBC (109/L)

6.1 ± 1.6

10.4 ± 7.2***

 RBC (1012/L)

4.8 ± 0.3

4.9 ± 0.5

 Hb (g/L)

139.3 ± 8.9

144.6 ± 11.8

 PLT (109/L)

236.3 ± 72.6

249.6 ± 68.6

 ESR (mm/h)

5.6 ± 2.3

19.2 ± 8.8***

 TC (mmol/L)

5.3 ± 0.4

4.9 ± 0.5

 TG (mmol/L)

1.2 ± 0.12

1.4 ± 0.13

 HDL (mmol/L)

1.0 ± 0.11

1.04 ± 0.08

 LDL (mmol/L)

2.95 ± 0.82

2.97 ± 0.72

 AI

2.7 ± 0.3

3.3 ± 0.4*

 IL-33 (pg/mL)

165 ± 25.6

283 ± 54.8***

 IL-1β (pg/mL)

23.5 ± 3.2

69.6 ± 3.4***

 IL-6 (pg/mL)

57.4 ± 6.8

122.8 ± 11.6***

 TNF-α (pg/mL)

29.5 ± 4.3

82.5 ± 7.9***

 IL-10 (pg/mL)

32.3 ± 5.2

68.4 ± 6.2***

  1. The data are presented as mean ± standard. *P < 0.05, ***P < 0.001 vs healthy controls
  2. AIS acute ischemic stroke, BMI body mass index, NIHSS National Institutes of Health Stroke Scale, CHD coronary heart disease, WBC white blood cells, RBC red blood cells, Hb hemoglobin, PLT platelets, ESR erythrocyte sedimentation rate, TC total cholesterol, TG triglycerides, HDL high-density lipoproteins, LDL low-density lipoproteins, AI atherogenic index, IL-33 interleukin-33, IL-1β interleukin-1β, IL-6 interleukin-6, TNF-α tumor necrosis factor-α, IL-10 interleukin-10