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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats

Fig. 5

Overexpression of AZGP1 suppressed the increase of TNFα and IL-6 in PTZ-kindled rats. a Representative western blot bands and expression level of TNFα in the hippocampal tissues of rats. Western blot showed increased level of TNFα in the hippocampal tissues of rats in GFP + PTZ group compared to controls, and rats in AZGP1 + PTZ group had significantly decreased the level of TNFα compared to GFP + PTZ group. b Representative western blot bands and expression level of IL-6 in the hippocampus of rats. Western blot showed increased level of IL-6 in the hippocampal tissues of rats in GFP + PTZ group compared to controls, and rats in AZGP1 + PTZ group had significantly decreased the level of IL-6 compared to GFP + PTZ group. Optic density normalized by GAPDH, n = 5 for each group, *p < 0.05

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