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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

Fig. 2

The effects of RO27-3225 on neurobehavioral outcomes and brain water content after ICH. a Modified Garcia test, b forelimb placement test, c corner turn test, and d brain water content at 24 h after ICH. e Modified Garcia test, f forelimb placement test, g corner turn test, and h brain water content at 72 h after ICH. *p < 0.05 vs. sham, #p < 0.05 vs. ICH + vehicle. Error bars are represented as mean ± SD. One-way ANOVA, Tukey’s test, n = 6 per group. RO RO27-3225, Ipsi-BG ipsilateral basal ganglia, Ipsi-CX ipsilateral cortex, Cont-BG contralateral basal ganglia, Cont-CX contralateral cortex, Cerebel cerebellum

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Journal of Neuroinflammation

ISSN: 1742-2094