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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

Fig. 4

The effects of RO27-3225 on long-term neurobehavioral outcomes after ICH. a Foot fault test and b Rotarod test in the first, second, and third week after ICH. c Escape latency and d swim distance of Morris water maze on days 21 to 25 after ICH. e Typical traces and f probe quadrant duration of Morris water maze on day 25 after ICH. *p < 0.05 vs. sham, #p < 0.05 vs. ICH + vehicle. Error bars are represented as mean ± SD. Two-way repeated measures ANOVA, Tukey’s test (a–d), and one-way ANOVA, Tukey’s test (f), n = 8 per group

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