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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice

Fig. 4

Galantamine prevented the reduction of synapse-associated proteins and neurodegeneration in the hippocampus of LPS-exposed mice. The protein levels of SYN (a) and PSD-95 (b) were examined by western blot. Data are reported as mean ± SEM (n = 5). Golgi silver-stained neurons in the hippocampal CA1 subfield (c). Representative images are shown (n = 3). Bar = 100 μm. d Representative dendritic spine and dendritic spine density at the CA1 hippocampal region (n = 3). Bar = 10 μm. **P < 0.01, ***P < 0.001, as compared with the control group; ##P < 0.01, ###P < 0.001, as compared with the LPS group

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