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Table 3 Uni- and multi-variate cox regression analysis of risk factors associated with relapse free survival

From: Platelet-derived growth factor predicts prolonged relapse-free period in multiple sclerosis

Univariable analysis HR 95% CI p value Multivariable analysis HR 95% CI p value
Age, years 0.93 0.89–0.97 0.001 Age, years 0.93 0.89–0.97 0.002
Escalation to second line: no 1 Reference category Escalation to second line: no 1 Reference category
Yes vs no 3.31 1.56–7.04 0.002 Yes vs no 2.7 1.18–6.18 0.018
PDGF groups: not detected PDGF 1 Reference category PDGF category: not detected PDGF 1 Reference category
Medium PDGF vs not detected PDGF 0.5 0.20–1.21 0.124 Medium PDGF vs not detected PDGF 0.28 0.10–0.79 0.017
High PDGF vs not detected PDGF 0.36 0.14–0.92 0.033 PDGF vs not detected PDGF 0.33 0.13–0.89 0.029
MRI progression: no 1 Reference category Not included in the multivariable final Cox regression model
Yes vs no 2.19 1.03–4.64 0.041
Sex: Male 1 Reference category
Female vs male 1 0.46–2.20 0.996
Disease duration, months 0.95 0.77–1.19 0.667
IL-12 0.99 0.99–1.00 0.137
GMCSF 1 0.99–1.01 0.908
FGF basic 0.99 0.95–1.03 0.555
GCSF 1.00 0.99–1.00 0.508
IL-10 0.99 0.98–1.01 0.328