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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway

Fig. 3

Knockdown of BLVRA aggravated GMH-induced inflammation. a Western blot analysis of BLVRA and inflammatory cytokine expression in BLVRA-treated and BLVRA-knockdown splenic tissues; representative blots are shown. b Quantitative analysis of BLVRA and inflammatory cytokine expression in BLVRA-treated and BLVRA-knockdown splenic tissues. c Western blot analysis of inflammatory cytokine expression in BLVRA-treated brain tissues; representative blots are shown. d Quantitative analysis of inflammatory cytokine expression in BLVRA-treated brain tissues. Values are expressed as mean ± SD. *P < 0.05 compared with sham, #P < 0.05 compared with GMH + vehicle. &P < 0.05 compared with GMH + BLVRA. %P < 0.05 compared with GMH + scrambled siRNA. N = 6 each group

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Journal of Neuroinflammation

ISSN: 1742-2094