Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway

Fig. 4

Inhibition of eNOS in BLVRA-treated rats abrogated the anti-inflammatory effects induced by BLVRA. a Western blot assay was used to analyze the expression of phosphorylated eNOS and eNOS in splenic tissues in BLVRA, BLVRA + eNOS inhibitor and BLVRA + iNOS inhibitor animals. b Quantitative analysis of phosphorylated eNOS and eNOS in spleen tissues in BLVRA, BLVRA + eNOS inhibitor and BLVRA + iNOS inhibitor animals. c Western blot analysis of inflammatory cytokine expression in BLVRA and BLVRA + eNOS inhibitor groups. d Quantitative analysis of inflammatory cytokine expression in BLVRA and BLVRA + eNOS inhibitor groups. Values are expressed as mean ± SD. *P < 0.05 compared with sham, #P < 0.05 compared with GMH + vehicle. &P < 0.05 compared with GMH + BLVRA. N = 6 each group

Back to article page