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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation

Fig. 3

The effect of IL-1β on cLTP-induced GluA1 insertion was mediated by the regulation of actin dynamics. a The expression of sGluA1 in unstimulated control cells and cells treated with cLTP in the presence or absence of IL-1β with or without jasplakinolide (200 nM). b Quantification of the images shown in a. Data are mean ± SEM from three independent experiments expressed in terms of control (*p < 0.05, ANOVA). c Cells transfected with GFP were stained by phallodin. d The expression of sGluA1 in unstimulated control cells and cells treated with cLTP in the presence or absence of latrunculin A (1 μM). e Quantification of the images shown in d. Data are mean ± SEM from three independent experiments expressed in terms of control (*p < 0.05, ANOVA)

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