Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G

Table 2 Associations between normalized initial glycans and inflammation markers

Glycans	CRP	TNF-α	MMP9	Inflammation
GP1	− 0.024	0.074	0.177**	+&
GP2	0.202**	0.071	0.039	+&
GP3	0.070	0.155*	− 0.141*	/
GP4	0.144*	0.185**	0.013	+#
GP5	− 0.187**	− 0.138*	− 0.219**	−#
GP6	0.202**	0.103	0.170**	+#
GP7	0.038	− 0.057	− 0.042	/
GP8	0.106	0.065	0.067	/
GP9	0.009	0.005	− 0.006	/
GP10	0.146*	− 0.008	0.198**	+#
GP11	0.178**	0.008	0.244**	+#
GP12	− 0.073	− 0.186**	− 0.051	/
GP13	− 0.014	− 0.046	− 0.065	−&
GP14	− 0.216**	− 0.198**	− 0.094	−#
GP15	− 0.072	− 0.159*	− 0.069	−&
GP16	0.073	0.017	0.108	/
GP17	− 0.084	− 0.110	− 0.077	/
GP18	− 0.156*	− 0.165*	− 0.036	−#
GP19	− 0.045	0.053	− 0.012	/
GP20	− 0.076	0.034	− 0.129	/
GP21	− 0.139*	− 0.057	− 0.025	/
GP22	0.012	0.025	0.044	/
GP23	− 0.201**	− 0.038	− 0.215**	−#
GP24	− 0.021	0.074	− 0.017	/

# there are more than two significant and consistent inflammation markers. & the result is a combination of previous studies. + the association between glycans and inflammation is positive. − the association between glycans and inflammation is negative. / the association between glycans and inflammation remains unclear. CRP C-reactive protein, TNF-α tumor necrosis factor-alpha, MMP9 matrix metalloproteinase-9
*Correlation is significant at the 0.05 level
**Correlation is significant at the 0.01 level

ISSN: 1742-2094