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Table 3 The change of glycans in diseases by UPLC

From: Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G

Glycans

CRC

UC

CD

SLE

RA

CKD

PD

HT

T2D

O

DL*

IS

GP1

↑

–

–

↑

↑

–

–

–

–

–

–

↑

GP2

↑

–

–

↑

↑

↑

–

–

–

–

↑

–

GP3

↑

–

–

–

–

–

–

–

–

–

–

–

GP4

↑

↑

↑

↑

–

–

–

↑

–

–

↑

–

GP5

↑

–

–

↑

–

–

↓

–

–

–

↑

↓

GP6

↑

↑

↑

↑

–

↑

–

↑

↑

–

↑

–

GP7

–

–

–

↑

–

–

–

–

–

–

–

–

GP8

↓

–

–

↓

–

–

↑

–

↓

–

–

↑

GP9

↓

↓

↓

↓

–

–

–

–

↓

–

–

–

GP10

↓

–

–

↑

–

–

–

–

↑

–

–

–

GP11

↓

–

–

–

–

–

–

–

↑

–

↑

–

GP12

↓

–

–

↑

–

–

–

↓

–

–

–

–

GP13

↓

–

–

–

–

–

–

↓

–

–

–

↓

GP14

↓

↓

↓

↓

–

↓

↑

↓

–

↓

↓

↓

GP15

↓

–

–

–

–

–

–

↓

–

–

–

↓

GP16

↑

–

–

↓

–

–

–

–

–

–

–

–

GP17

–

–

–

↑

–

–

↓

–

–

–

–

↓

GP18

↓

↓

↓

↓

–

↓

–

↓

–

↓

↓

↓

GP19

↓

–

↓

↑

–

–

–

–

–

–

–

–

GP20

–

–

–

–

–

–

↓

–

–

–

↑

–

GP21

–

–

–

–

–

–

↓

–

–

–

↑

↓

GP22

↓

–

–

↑

↓

–

↓

–

–

–

–

–

GP23

–

–

–

↓

–

–

–

–

–

–

–

↓

GP24

–

–

–

↑

↑

–

–

–

–

–

–

–

Galactosylation

↓

↓

↓

↓

↓

↓

↓

↓

↓

↓

↓

↓

Sialylation

↓

–

↓

↓

–

↓

↓

↓

↓

–

↓

↓

Fucosylation

↑

–

–

↓

↑

–

–

↓

↓

–

–

–

Bisecting GlcNAc

↓

–

↑

↑

–

↑

–

↑

↑

–

↑

↑

  1. ↑ high level of glycans can increase the risk of disease. ↓ low level of glycans can increase the risk of disease. CRC colorectal cancer, UC ulcerative colitis, CD Crohn’s disease, SLE systemic lupus erythematosus, RA rheumatoid arthritis, CKD chronic kidney disease, PD Parkinson’s disease, HT hypertension, T2D type 2 diabetes, O obesity, DL dyslipidemia, IS ischemic stroke
  2. *Unpublished paper