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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Evidence of the impact of systemic inflammation on neuroinflammation from a non-bacterial endotoxin animal model

Fig. 6

Perioperative ibuprofen intervention prevented cognitive dysfunction. a Percentage body weight changes with and without ibuprofen administration. Two-way ANOVA followed by Bonferroni’s post hoc test (***p = 0.0001, F1,108 = 20.06). b Reduction in DI decline in the NOR test after laparotomy with ibuprofen treatment. ***p = 0.0002, t = 4.301; Student’s two-tailed t test. c Reduced error number, Mann-Whitney test, Mann-Whitney U statistic = 14, **p = 0.0029, and shorter latency in the Y-maze test, *p = 0.0142, t = 2.698; Student’s two-tailed t test. ac n = 11 in LAP group and n = 14 in LAP+Ibu group

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