Fig. 4From: Anti-high mobility group box 1 antibody suppresses local inflammatory reaction and facilitates olfactory nerve recovery following injuryEffects of anti-HMGB1 antibody on recovery from olfactory NTx injury. Histological sections illustrating control IgG (50 μg, a)- and anti-HMGB1 antibody (50 μg, b)-injected mice at 100 days after NTx injury. Calibration bar = 500 μm. Quantitative measurements showing the time course and comparison of changes in the amount of injury-associated tissue (c) and X-gal stained olfactory nerve innervation to the glomerular layer on the olfactory bulb (d) for anti-HMGB1 antibody (low and high doses) and control IgG animals. Asterisk (*) and section sign (§) indicate significant differences (*p < 0.016, §p < 0.0005) compared to the control IgG groupBack to article page