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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor α, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells

Fig. 2

ACKR3 mRNA and protein expression in HBMEC after co-stimulation with LPS and Ureaplasma spp. ACKR3 mRNA expression was assessed using qRT-PCR (a) and RNA sequencing (b). Protein expression was determined by flow cytometry, with (c) representing the percentage of ACKR3- and CD31-positive HBMEC, and (d) depicting representative dot plots, both after a stimulation period of 48 h. Dot plots were gated for vital cells. Data are shown as mean ± SD (p values after logarithmic transformation, °°p < 0.01, °°°p < 0.001 vs. broth; #p < 0.05, ##p < 0.01 vs. LPS; §p < 0.05, §§p < 0.01 vs. broth + LPS; $$p < 0.01 vs. isolate alone)

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