Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke

Fig. 6

The effect of splenectomy on peripheral lymphocytes before RIPC and MCAO. a Experimental protocols. Two groups of animals were adopted: non-splenectomy + RIPC + MCAO and splenectomy + RIPC + MCAO. Blood was collected from the caudal tail vein at 1 h after preconditioning ( and ) and 3 days after brain reperfusion ( and ). bd Flow cytometry analysis of B lymphocytes. ei Flow cytometry analysis of T lymphocyte subsets. - reflects the change of lymphocyte populations prior to and after RIPC + MCAO without splenectomy; - reflects the change of lymphocyte populations prior to and after MCAO with splenectomy and RIPC. Data are expressed as means ± SEM for 12 independent experiments. *p < 0.05, **p < 0.01 versus or -; #p < 0.05, ##p < 0.01 versus

Back to article page