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Table 1 Lymphocyte subsets in blood and CSF samples obtained prior to treatment for rheumatoid meningitis

From: Rheumatoid meningitis developed in patient with stable rheumatoid arthritis and myasthenia gravis—detailed analysis of intracranial inflammation using flow cytometry

Lymphocyte subset

Function

Blood (%)

Viral meningitis

CSF (%)

Viral meningitis

CD3

Mature T cell

55.6

75.0 ± 7.4

88.8

86.7 ± 8.7

CD4

Helper T cell

40.2

41.4 ± 11.1

81.5

66.3 ± 10.2

CD8

Suppressor/cytotoxic T cell

16.2

33.0 ± 14.3

7.1

21.6 ± 8.4

CD19

B cell

26.7

9.2 ± 3.8

3.8

3.7 ± 6.5

CD3-CD16+CD56+

NK cell

18.9

13.9 ± 6.6

5.3

6.3 ± 4.1

CD4+CD29+

Helper-inducer T cell

19.8

17.7 ± 4.8

69.2

47.7 ± 12.2

CD4+CCR5+

Th1 cell

2.4

3.2 ± 1.6

21.4

16.3 ± 13.3

CD4+CXCR3+

Th1 cell

8.7

11.7 ± 3.7

37.6

41.3 ± 13.0

CD4+CCR3+

Th2 cell

11.4

1.4 ± 1.7

38.3

8.5 ± 16.4

CD4+CCR4+

Th2 cell

1.3

3.1 ± 2.5

10.4

10.4 ± 15.2

CD4/8

 

2.50

 

11.50

 
  1. Values for viral meningitis were adopted from the results of a previous study, designated as [10]
  2. CSF cerebrospinal fluid, NK natural killer, Th1 type 1 helper T, Th2 type 2 helper T