Fig. 7From: Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasomeEffects of SN on the expression of hippocampal inflammatory cytokines in PTZ kindled rats. Representative immunoreactive bands and statistical results showing SN alone has no influence on the expression of IL-1β (a), IL-18 (c), IL-6 (e), and TNF-α (g) in protein level. Representative immunoreactive bands and statistical results showing SN dose-dependently inhibited PTZ-induced increase in the expression of IL-1β (b), IL-18 (d), IL-6 (f), and TNF-α (h) in protein level. Data are expressed as means ± SEM. n = 6–8, ##P < 0.01 vs control and *P < 0.05 and **P < 0.01 vs PTZBack to article page