Inflammation leads to distinct populations of extracellular vesicles from microglia

Yang, Yiyi; Boza-Serrano, Antonio; Dunning, Christopher J. R.; Clausen, Bettina Hjelm; Lambertsen, Kate Lykke; Deierborg, Tomas

doi:10.1186/s12974-018-1204-7

Journal of Neuroinflammation

Table 2 List of proteins identified in LPS EV samples

From: Inflammation leads to distinct populations of extracellular vesicles from microglia

Protein ID	Gene name	Protein name	Score
P68372	TUBB4B	Tubulin beta-4B chain	258
P62242	RPS8	40S ribosomal protein S8	201
P47963	RPL13	60S ribosomal protein L13	181
Q9CZX8	RPS19	40S ribosomal protein S19	178
P15864	HIST1H1C	Histone H1.2	172
Q8VEK3	HNRNPU	Heterogeneous nuclear ribonucleoprotein U	148
Q9CR57	RPL14	60S ribosomal protein L14	146
P63276	RPS17	40S ribosomal protein S17	138
P11152	LPL	Lipoprotein lipase	130
P16858	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase	128
P68369	TUBA1A	Tubulin alpha-1A chain	123
P62082	RPS7	40S ribosomal protein S7	106
Q9D8E6	RPL4	60S ribosomal protein L4	101
P35979	RPL12	60S ribosomal protein L12	101
P14131	RPS16	40S ribosomal protein S16	100
P70696	HIST1H2BA	Histone H2B type 1-A	100
P12970	RPL7A	60S ribosomal protein L7a	98
P60710	ACTB	Actin, cytoplasmic 1	94
Q9CXW4	RPL11	60S ribosomal protein L11	85
Q9CZM2	RPL15	60S ribosomal protein L15	84
P02301	H3F3C	Histone H3.3C	83
P47911	RPL6	60S ribosomal protein L6	83
P43276	HIST1H1B	Histone H1.5	83
Q8CGP5	HIST1H2AF	Histone H2A type 1-F	82
P14115	RPL27A	60S ribosomal protein L27a	74
P27659	RPL3	60S ribosomal protein L3	72
O55142	RPL35A	60S ribosomal protein L35a	70
P25206	MCM3	DNA replication licensing factor MCM3	68
P62702	RPS4X	40S ribosomal protein S4, X isoform	63
P10126	EEF1A1	Elongation factor 1-alpha 1	63
Q8BP67	RPL24	60S ribosomal protein L24	62
P14206	RPSA	40S ribosomal protein SA	62
P11499	HSP90AB1	Heat shock protein HSP 90-beta	60
P08226	APOE	Apolipoprotein E	60
P35980	RPL18	60S ribosomal protein L18	59
P63017	HSPA8	Heat shock protein 8	59
P80318	CCT3	T-complex protein 1 subunit gamma	58
P62918	RPL8	60S ribosomal protein L8	57
O08585	CLTA	Clathrin light chain A	55
Q9Z1Q9	VARS	Valine-tRNA ligase	54
P01942	HBA	Hemoglobin subunit alpha	51
P97351	RPS3A	40S ribosomal protein S3a	50
P62806	HIST1H4A	Histone H4	48
P62270	RPS18	40S ribosomal protein S18	44
P62911	RPL32	60S ribosomal protein L32	43
P14869	RPLP0	60S acidic ribosomal protein P0	41
Q9JIK5	DDX21	Nucleolar RNA helicase 2	41
P62281	RPS11	40S ribosomal protein S11	41
Q68FD5	CLTC	Clathrin heavy chain 1	40
P62717	RPL18A	60S ribosomal protein L18a	39
P86048	RPL10L	60S ribosomal protein L10-like	39
P62267	RPS23	40S ribosomal protein S23	37
P25444	RPS2	40S ribosomal protein S2	36
P14148	RPL7	60S ribosomal protein L7	31
P53026	RPL10A	60S ribosomal protein L10a	28
P62264	RPS14	40S ribosomal protein S14	28
P62908	RPS3	40S ribosomal protein S3	23
P04918	SAA3	Serum amyloid A-3 protein	23

Proteins retrieved in LPS extracellular vesicles samples from mass spectrometry. Protein ID and gene name are according to Uniprot Knowledgebase. Score values were obtained using MASCOT. The score shows how well the observed protein matches to the stated protein in the database. Only protein identifications supported by at least two high confident peptides (confidence > 95%) were considered

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ISSN: 1742-2094

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