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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Chronic constriction injury-induced microRNA-146a-5p alleviates neuropathic pain through suppression of IRAK1/TRAF6 signaling pathway

Fig. 3

Expression and cellular distributions of TRAF6 in rat DRG after CCI. a qPCR showing the time course for TRAF6 level in DRG (n = 4 in each group). One-way ANOVA, *P < 0.05, versus sham. b Western blot analyzes the time course for TRAF6 expression in DRG. c Cellular distribution of TRAF6 in rat DRGs of sham, CCI 7 days, CCI 14 days, and CCI 21 day. d Percentage of TRAF6-positive neurons in DRGs of sham, CCI (7 days), CCI (14 days), and CCI (21 days) rats. n = 4 in each group, One-way ANOVA, *P < 0.05, versus sham. e Double immunostaining showing co-expression of TRAF6 (green) with CGRP (red) in rat DRG of CCI 14 day. f Double immunostaining showing co-expression of TRAF6 (green) with IB4 (red) in rat DRG of CCI 14 days. Scale bar 25 μm in c, e, and f

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Journal of Neuroinflammation

ISSN: 1742-2094