Fig. 8From: Bone marrow-derived mesenchymal stem/stromal cells reverse the sensorial diabetic neuropathy via modulation of spinal neuroinflammatory cascadesMSC transplantation modulates cytokine expression in the spinal cord of mice with diabetic neuropathy. Four weeks after the neuropathy induction, mice were treated with MSC (1 × 106; STZ + MSC) or saline (STZ + saline) via endovenous route. Control group received saline instead of streptozotocin. Spinal cytokine levels were evaluated before, 2 and 8 weeks after treatments. Panels show the spinal levels of a interleukin-1β (IL-1β), b tumor necrosis factor-α (TNF-α), c interleukin-10 (IL-10), and d transforming growth factor-β (TGF-β). The results are expressed as picograms of cytokine per milligram of protein. Data are expressed as means ± SEM; n = 6 mice per group. *Statistically significant as compared to the control group (p < 0.001). #Statistical significance in relation to the STZ + saline group (p < 0.05). One-way ANOVA followed by Tukey’s multiple comparison testBack to article page