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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

Fig. 2

Co-infection in the lung activates microglia. Brain sections containing paraventricular ventricle (PVN) from saline (SAL), S. pneumoniae (SP), influenza A virus (IAV) or co-infection (SPIAV)-treated mice were immunolabelled for astrocytic marker GFAP (a) and GFAP-positive area were quantified (b). Microglia were stained with Iba-1 antibody (c), and Iba-1-positive area was quantified (d). Number of ameboid microglia within the PVN was manually counted (e). n = 5–6 with 3–4 sections from each brain; *p < 0.05, one-way ANOVA compared to SAL

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