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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

Fig. 4

Co-infection facilitates greater pneumococcal entry into the CNS. Olfactory epithelium, olfactory bulb and hypothalamus were dissected from mice with saline (SAL), S. pneumoniae (SP), influenza A virus (IAV) or co-infection (SPIAV) treatment. Titres of influenza A viruses and S. pneumoniae in these tissues were measured in (ac) and (df) respectively. Dashed lines denote detection limits. n = 6; *p < 0.05, two-tailed Students unpaired t tests

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