The splenic response to stroke: from rodents to stroke subjects

Table 1 Studies looking at the splenic response to stroke

		Species	Type	Duration	Citation
Observations	Splenocyte apoptosis	Mus	tMCAO	96 h	[20]
	Increased IFNg levels	Mus	tMCAO	96 h	[8]
	Increased IFNg levels	Rat	pMCAO	96 h	[7, 24]
	Splenic contraction	Rat	pMCAO	96 h	[7]
	Change in spleen size	Hu	Ischemic	Variable	[39]
	Change in spleen size	Hu	Ischemic hemorrhagic	Variable	[40]
	Splenic contraction (some subjects)	Hu	Ischemic hemorrhagic	Variable	[41]
	SIRS with splenic contraction (some subjects)	Hu	Ischemic	Variable	[42]
Pre-treatment	Splenectomy protection (males only)	Mus	tMCAO	96 h	[9]
	Splenectomy protection	Mus	tMCAO	96 h	[8]
		Rat	pMCAO	96 h	[6]
		Rat	ICH	72 h	[10]
	Carvedilol	Rat	pMCAO	48 h	[18]
Post-treatment	RTL	Mus	tMCAO	96 h	[36,37,38]
	Splenic irradiation	Rat	tMCAO	48 h, 7 days	[31]
	HUCBC’s	Rat	pMCAO	48 h, 96 h	[19, 32,33,34]
	NSC	Rat	ICH	72 h	[10]

This table summarizes experiments that involve the splenic response in stroke. Some observational studies, some pre-treatment studies, some post-treatment studies. Studies with mice, rats, and human stroke subjects are included

ISSN: 1742-2094