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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain

Fig. 8

Role of TLR4 and GSK3β in EtOH-induced inflammation. SIM-A9 cells were pretreated with TAK242 (1 μM) or SB-216763 (10 μM) for 12 h, then exposed to EtOH (0.4%) for 12 h. The expression of Iba-1, TNFα, and IL-6 was determined by IB and quantified by the normalization to the expression of actin. Each data point the mean ± SEM of three independent experiments. *p < 0.05, statistically significant difference from control group; #p < 0.05, statistically significant difference from EtOH-treated group

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Journal of Neuroinflammation

ISSN: 1742-2094