Table 2 Plasma and CSF cytokines of the interruption and initiation cohorts over time
From: Brain 18F-FDG PET of SIV-infected macaques after treatment interruption or initiation
| Â | Interruption | Initiation | |||||||
|---|---|---|---|---|---|---|---|---|---|
Baseline | Month 1 | Month 3 | Month 6 | Baseline | Month 1 | Month 3 | Month 6 | ||
Plasma | IL-2 | 5.51 (4.07) | 4.25 (5.49) | 5.75 (4.349) | 2.62 (3.70) | 9.10 (6.80) | 5.63 (3.88) | 5.82 (4.27) | 5.85 (2.49) |
IL-10 | 2.98 (6.66) | 2.98 (6.66) | 2.98 (6.67) | 3.56 (5.03) | 8.07 (18.04) | 0 (0) | 1.22 (2.73) | 0 (0) | |
IL-15 | 5.14 (4.44) | 4.67 (4.22) | 5.55 (1.95) | 3.98 (0.37) | 7.14 (4.16) | 3.94 (4.14) | 4.98 (2.10) | 4.83 (3.60) | |
IL-8 | 25.59 (20.38) | 26.65 (12.01) | 77.25 (103.80) | 22.61 (8.60) | 144.60 (111.00) | 18.70 (12.07) | 38.39 (25.30) | 20.10 (15.11) | |
IL-1Ra | 40.49 (58.85) | 38.41 (53.41) | 37.48 (42.52) | 19.16 (9.24) | 26.43 (14.19) | 18.73 (9.73) | 14.14 (8.96) | 17.03 (13.65) | |
MCP-1 | 240.3 (65.4) | 217.9 (78.7) | 204.4 (70.1) | 245.5 (182.2) | 349.5 (287.8) | 266.2 (140.9) | 254.1 (190.5) | 270.4 (139.4) | |
CSF | IL-2 | 16.49 (10.89) | 26.28 (23.52) | 28.19 (6.96) | 32.87 (12.38) | 21.25 (14.25) | 19.49 (6.29) | 23.49 (6.20) | 22.81 (8.09) |
IL-10 | 20.89 (13.37) | 40.67 (31.34) | 35.61 (8.29) | 43.68 (18.27) | 29.83 (17.83) | 33.63 (13.12) | 34.61 (6.65) | 28.72 (15.97) | |
IL-15 | 14.65 (2.93) | 16.14 (3.64) | 16.54 (5.01) | 21.37 (1.65) | 19.58 (3.01) | 16.83 (2.90) | 14.60 (1.53) | 18.24 (4.49) | |
IL-8 | 10.50 (3.71) | 21.23 (21.2) | 14.84 (3.40) | 25.1 (0.17) | 13.61 (4.30) | 8.80 (6.58) | 10.43 (4.13) | 7.90 (2.22) | |
IL-1Ra | 0.92 (1.85) | 5.39 (6.30) | 7.13 (4.55) | 8.97 (2.73) | 8.27 (1.65) | 2.20 (4.39) | 3.19 (5.53) | 1.76 (3.05) | |
MCP-1 | 446.7 (76.0) | 947.2 (1070.0) | 617.1 (153.7) | 702.8 (303.5) | 641.1 (141.4) | 422.2 (121.1) | 526.6 (137.6) | 481.0 (127.6) | |