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Table 2 Plasma and CSF cytokines of the interruption and initiation cohorts over time

From: Brain 18F-FDG PET of SIV-infected macaques after treatment interruption or initiation

  Interruption Initiation
Baseline Month 1 Month 3 Month 6 Baseline Month 1 Month 3 Month 6
Plasma IL-2 5.51 (4.07) 4.25 (5.49) 5.75 (4.349) 2.62 (3.70) 9.10 (6.80) 5.63 (3.88) 5.82 (4.27) 5.85 (2.49)
IL-10 2.98 (6.66) 2.98 (6.66) 2.98 (6.67) 3.56 (5.03) 8.07 (18.04) 0 (0) 1.22 (2.73) 0 (0)
IL-15 5.14 (4.44) 4.67 (4.22) 5.55 (1.95) 3.98 (0.37) 7.14 (4.16) 3.94 (4.14) 4.98 (2.10) 4.83 (3.60)
IL-8 25.59 (20.38) 26.65 (12.01) 77.25 (103.80) 22.61 (8.60) 144.60 (111.00) 18.70 (12.07) 38.39 (25.30) 20.10 (15.11)
IL-1Ra 40.49 (58.85) 38.41 (53.41) 37.48 (42.52) 19.16 (9.24) 26.43 (14.19) 18.73 (9.73) 14.14 (8.96) 17.03 (13.65)
MCP-1 240.3 (65.4) 217.9 (78.7) 204.4 (70.1) 245.5 (182.2) 349.5 (287.8) 266.2 (140.9) 254.1 (190.5) 270.4 (139.4)
CSF IL-2 16.49 (10.89) 26.28 (23.52) 28.19 (6.96) 32.87 (12.38) 21.25 (14.25) 19.49 (6.29) 23.49 (6.20) 22.81 (8.09)
IL-10 20.89 (13.37) 40.67 (31.34) 35.61 (8.29) 43.68 (18.27) 29.83 (17.83) 33.63 (13.12) 34.61 (6.65) 28.72 (15.97)
IL-15 14.65 (2.93) 16.14 (3.64) 16.54 (5.01) 21.37 (1.65) 19.58 (3.01) 16.83 (2.90) 14.60 (1.53) 18.24 (4.49)
IL-8 10.50 (3.71) 21.23 (21.2) 14.84 (3.40) 25.1 (0.17) 13.61 (4.30) 8.80 (6.58) 10.43 (4.13) 7.90 (2.22)
IL-1Ra 0.92 (1.85) 5.39 (6.30) 7.13 (4.55) 8.97 (2.73) 8.27 (1.65) 2.20 (4.39) 3.19 (5.53) 1.76 (3.05)
MCP-1 446.7 (76.0) 947.2 (1070.0) 617.1 (153.7) 702.8 (303.5) 641.1 (141.4) 422.2 (121.1) 526.6 (137.6) 481.0 (127.6)
  1. Data are shown as mean values with standard deviations in parentheses