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Table 1 Clinical findings of human samples used for RT-qPCR and in situ hybridization

From: Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes

Experiment

Pathology

n

Age

Gender m/f

HS ILAE*

Type 1/type 2

Duration of epilepsy (years)

Age at onset

Number of seizures

(per month)

RT-qPCR

Control

6

63 (25–86)

4/2

–

–

–

–

TLE-HS

16

35 (24–49)

9/7

12/4

20 (5–41)

15 (3–34)

19 (1–36)

ISH

Control

5

48 (31–64)

3/2

–

–

–

–

TLE-HS

10

35 (24–49)

7/3

7/3

20 (5–41)

16 (3–34)

13 (2–32)

  1. TLE temporal lobe epilepsy, HS hippocampal sclerosis, ISH in situ hybridization, m male, f female. Values are given as mean (minimum–maximum)
  2. *According to Blümcke et al. 2013 [53]
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Journal of Neuroinflammation

ISSN: 1742-2094