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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

Fig. 6

Treg-induced inhibition of Teff proliferation in HS and PD patients. Teff from HS and PD patients proliferated to a similar extent in the presence of PHA (a) and were concentration-dependently inhibited by Treg (b). Treg inhibition of Teff proliferation was reduced by DA 1 μM in cells from HS and PD-dn patients but not from PD-dt patients (c). Data are means ± SD of n = 9–17 subjects. *P < 0.05 and **P < 0.01 vs respective Teff alone; #P < 0.05 vs respective Teff:Treg 1:1; §P < 0.05 vs both HS and PD-dn

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