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Table 1 Characteristics of HS and PD patients enrolled in study #1. Data are means ± SD unless otherwise indicated

From: Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

 

HS

PD-dn

PD-dt

P

HS vs PD-dn

HS vs PD-dt

PD-dn vs PD-dt

n47

26

56

Gender (M/F)

25/22

15/11

34/22

0.808

0.549

0.813

Age (years)

66.8 ± 10.3

68.0 ± 9.3

70.4 ± 8.5

0.632

0.057

0.254

UPDRS part III (score)

13.6 ± 7.2

15.3 ± 6.6

0.101

 1–10 (n)

14

13

0.010

 11–20 (n)

7

34

  > 20 (n)

5

9

H&Y scale (stage)

1.3 ± 0.5

1.9 ± 0.7

0.001

 1.0 (n)

16

14

0.004

 1.5–2.0 (n)

9

31

  > 2.5 (n)

1

11

LED (mg/day)

533.2 ± 360.1

Drugs

l-DOPA (n)

45a

DA agonists (n)

36b

 Pramipexole (n)

23

 Ropinirole (n)

5

 Rotigotine (n)

8

Rasagiline (n)

21

  1. a11 taking l-DOPA alone, and 34 taking l-DOPA + DA agents
  2. b9 taking DA agonists alone (4) or with rasagiline (5), and 34 taking DA agonists + l-DOPA, without (19) or with rasagiline (15)
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Journal of Neuroinflammation

ISSN: 1742-2094