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Table 1 Characteristics of HS and PD patients enrolled in study #1. Data are means ± SD unless otherwise indicated

From: Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients

  HS PD-dn PD-dt P
HS vs PD-dn HS vs PD-dt PD-dn vs PD-dt
n47 26 56
Gender (M/F) 25/22 15/11 34/22 0.808 0.549 0.813
Age (years) 66.8 ± 10.3 68.0 ± 9.3 70.4 ± 8.5 0.632 0.057 0.254
UPDRS part III (score) 13.6 ± 7.2 15.3 ± 6.6 0.101
 1–10 (n) 14 13 0.010
 11–20 (n) 7 34
  > 20 (n) 5 9
H&Y scale (stage) 1.3 ± 0.5 1.9 ± 0.7 0.001
 1.0 (n) 16 14 0.004
 1.5–2.0 (n) 9 31
  > 2.5 (n) 1 11
LED (mg/day) 533.2 ± 360.1
Drugs
l-DOPA (n) 45a
DA agonists (n) 36b
 Pramipexole (n) 23
 Ropinirole (n) 5
 Rotigotine (n) 8
Rasagiline (n) 21
  1. a11 taking l-DOPA alone, and 34 taking l-DOPA + DA agents
  2. b9 taking DA agonists alone (4) or with rasagiline (5), and 34 taking DA agonists + l-DOPA, without (19) or with rasagiline (15)