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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model

Fig. 10

Similar microglial activation in MPTP-treated WT and Cx30 KO. WT and Cx30 KO mice were injected with normal saline (NS) or MPTP and analysed on day 1 or 7 after treatment. a, b Number of Iba1-positive cells in the striatum (a) and SNc (b) of WT and Cx30 KO mice on day 1. c, d Iba1 immunostaining of the striatum and SNc on days 1 (c) and 7 (d) after treatment. Data are expressed as the mean ± SEM of n = 4 mice per group. N.S., not significant; ***p < 0.001 by two-way ANOVA followed by the Tukey–Kramer post hoc test. Scale bars: striatum, 200 μm; SNc, 100 μm

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Journal of Neuroinflammation

ISSN: 1742-2094