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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model

Fig. 6

Microarray gene expression analysis of A1, A2, and pan-reactive astrocyte gene sets at day 1 after MPTP treatment. a Scatter plots. Black arrows show the genes that were validated by RT-PCR. The X- and Y-axis values are the log10 scale-normalised signals. b Enrichment plots (green curve) show the running sum of the enrichment score (ES) for each gene set. The score at the peak of the plots is the ES for each gene set. The black bars show where the members of the gene set appear in the ranked list of genes. A predominance of black bars to the left or right side indicates that most genes are upregulated in MPTP-treated WT mice or MPTP-treated Cx30 KO mice, respectively

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Journal of Neuroinflammation

ISSN: 1742-2094