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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Fas-ligand and interleukin-6 in the cerebrospinal fluid are early predictors of hypoxic-ischemic encephalopathy and long-term outcomes after birth asphyxia in term infants

Fig. 4

Receiver-operator characteristic (ROC) curve of Fas-ligand (FasL) and interleukin-6 (IL-6) in relation to hypoxic-ischemic encephalopathy (HIE) grade. Control and HIE I versus HIE grade II–III. a The AUC for FasL was 0.89. The FasL cutoff value of 24 pg/mL (dashed lines) predicted HIE grade with a sensitivity of 90.0% and a specificity of 82.4%. b The AUC for IL-6 was 0.87. At the cutoff value of 77 pg/mL (dashed lines), IL-6 predicted HIE grade with a sensitivity of 66.7% and a specificity of 94.1%. c Using a combination of ranks for IL-6 and Fas-L, the sensitivity was 86.7% and specificity 91.2% in relation to degree of HIE. The sum for ranking of IL-6 and Fas-L was used for the evaluation. The AUC for the sum for ranking was 0.94

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