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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Fas-ligand and interleukin-6 in the cerebrospinal fluid are early predictors of hypoxic-ischemic encephalopathy and long-term outcomes after birth asphyxia in term infants

Fig. 5

Receiver-operator characteristic (ROC) curve of Fas-ligand (FasL) and interleukin-6 (IL-6) in relation to adverse outcome. Adverse outcome is defined as adverse neurological outcome at the 18-month assessment or death. a The AUC for FasL was 0.86. The FasL cutoff value of 45 pg/mL (dashed lines) predicted adverse outcomes with a sensitivity of 79.2% and a specificity of 82.5%. b The AUC for IL-6 was 0.90. The IL-6 cutoff value of 77 pg/mL (dashed lines) predicted adverse outcomes with a sensitivity of 79.2% and a specificity of 92.5%. c Using a combination of ranks for IL-6 and Fas-L, the sensitivity was 95.8% and specificity 85.7% in relation to outcome. The sum for ranking of IL-6 and Fas-L was used for the evaluation. The AUC for the sum for ranking was 0.94

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Journal of Neuroinflammation

ISSN: 1742-2094