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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system

Fig. 2

Methylprednisolone treatment diminishes acute cytokine production. a Expression of selected inflammatory and anti-inflammatory cytokines was measured in the spinal cord at 24 h after decompression using a Luminex assay. Overall, MP treatment significantly decreased the levels of IL-1α (*p < 0.05). b Immunohistological analysis of the number of Iba1+ cells around the C5-C7 region at 2 weeks after decompression. Their number in the dorsal and ventral horns showed a non-significant reduction after MP treatment. Representative images for each treatment group are shown as well as a schematic of a spinal cord depicting the area analyzed. The white arrows indicate Iba1+ cells in the spinal cord. Data were analyzed using an unpaired Student’s t test and are presented as mean ± SEM

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