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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Cell permeable HMGB1-binding heptamer peptide ameliorates neurovascular complications associated with thrombolytic therapy in rats with transient ischemic stroke

Fig. 3

HBHP decreased the mortality of 4.5 h MCAO rats with tPA administration. a Schematic diagram of the overall experimental design. b The 24 h survival curves of rats with 2 h or 4.5 h MCAO treated with vehicle or tPA in combination of HBHP or scramble peptide. The rat number in each group was labeled. c The mortality of each group rats at 24 h post ischemia. Numbers in parentheses mean “the dead rats/the total number of rats” in each group. NS: not significant; *P < 0.05

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