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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Cell permeable HMGB1-binding heptamer peptide ameliorates neurovascular complications associated with thrombolytic therapy in rats with transient ischemic stroke

Fig. 7

HBHP alleviated inflammatory reactions in tPA-treated stroke rats. a ELISA data of serum IL-1β levels in stroke rats at 8 h after ischemia, n = 5–7. b Quantitative real-time PCR analysis of mRNA expressions of IL-1β, IL-6, IL-12b, and TNF-α in the peri-infarct cortex from 4.5 h MCAO rats or in the same regions of sham-operated rats, n = 3–4. c Western blot and quantified data of iNOS, COX-2, and IL-1β in ischemic ipsilateral hemispheres at 8 h after ischemia, n = 3–4. NS: not significant; *P < 0.05. Data were shown as mean ± SD

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