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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats

Fig. 4

IVIg prevents mechanical allodynia induced by BTZ. Time course of paw withdrawal thresholds in the different groups. Until week 3 from the beginning of the study, rats eventually belonging to the therapeutic schedule group are reported together with the animals of the BTZ group. At the determination performed after 4 weeks, the animals of the therapeutic group had not yet received the first IVIg infusion. Data are reported as mean ± SEM. *p < 0.01 vs BTZ; **p < 0.05 vs BTZ

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