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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior

Fig. 4

ITGB4−/− mice show mania-like behavior. a Representative tracking data for ITGB4−/− (n = 10) and control (n = 9) mice during the 5-min open-field test. b, c ITGB4−/− mice traveled further in the 5-min open-field test and spent more time in the central area. d Representative tracking paths for ITGB4−/− and WT mice during the elevated plus maze test (EPM). e, f ITGB4−/− mice (n = 9) entered the open arms of the elevated plus maze more frequently and explored the open arm for a longer duration than control mice (n = 8). All data are presented as mean ± SEM. *p < 0.05, **p < 0.01

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