Fig. 4
From: The role of neutrophil granule proteins in neuroinflammation and Alzheimer’s disease
Sites of Aβ1–42 cleavage by Aβ degrading proteases. The amino acid sequence of Aβ1–42 is shown indicating the sites at which neprilysin (NEP, black arrows), endothelin-converting enzyme (E, blue arrows), neutrophil elastase (NE, red arrows), plasmin (P, pink arrows), cathepsin G (CG, orange arrows), insulin-degrading enzyme (I, purple arrows), and CAP37 (C, green arrows) cleave Aβ1–42. Asterisks (*) represent sites that are cleaved only by CAP37, neutrophil elastase, or cathepsin G