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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice

Fig. 1

Experimental set up and expression of CSF1R in mouse hippocampus: 12-month-old WT and APP-PS1 animals were treated for a total of 28 days with PLX5622 or control chow followed by behavior tests after 20 days of treatment (a). Qualitative immunohistochemical staining for CSF1R receptor (red) showed high-receptor expression in Iba1+ cells (white) in all studied groups (b). ThioflavinS was used to stain amyloid plaques (green), and Dapi (blue) was used as nucleus stain. Scale: 50 μm

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